Lymphocyte Activation Lab

Lymphocyte Activation Lab

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T and B lymphocytes, vital for our health, form the adaptive immune system. We investigate the regulation of B lymphocyte activation that mounts specific and highly effective antibody responses against pathogens. However, if lymphocyte activation is defected, we face pathological conditions such as autoimmunity or lymphoma. In our research, we integrate advanced light microscopy and proteomic approaches with cellular and in vivo models, to gain novel understanding on the cell biological phenomena of B cell activation.


Our work would not be possible without the critical support from these organizations:

 

Recent News

A new Mattila baby in the lab

We welcome a new Master’s thesis student, Julia Rantala! Julia will join Pinja to unravel the mysteries of Yellow fever immunity in B cells 😊 Read More "A new Mattila baby in the lab"

Fresh paper to start the year

In our latest paper, ”Enhanced antibody responses in CD19-Cre mice”, we report augmented antibody levels in B cell-specific CD19-Cre mouse model and promote careful consideration in the use of this common Cre-model line in B cell research.   Read More "Fresh paper to start the year"

Pikkujoulu lab outing

The Mattila lab embraced the holiday spirit in a thrilling way this year—by battling it out in an intense game of LaserTag! The competition was fierce but the fun was absolutely unmatched. It was the perfect opportunity to come together, recharge, and celebrate the season as a team. Here's to... Read More "Pikkujoulu lab outing"

Funding secured by Blanca!

Massive congratulations for Blanca for securing 1,5 years of UTU graduate school funding to finalize her PhD. Read More "Funding secured by Blanca!"