We are thrilled to announce that our article titled “A specific hybridisation internalisation probe (SHIP) enables precise live-cell and super-resolution imaging of internalized cargo”, has been published in Scientific Reports. The article can be found here.
The specific hybridization internalisation probe (SHIP) assay, developed for flow cytometry studies, employs a ssDNA fluorescence internalisation probe and a complementary ssDNA quenching probe to unambiguously detect the internalized receptors/cargo. We take advantage of the SHIP assay to study the trafficking of receptor/ligand complexes using B lymphocytes and B cell receptor-mediated antigen internalization as a model system.
Our article has been included in the “Editor’s choice: super-resolution microscopy” which highlights the versatility and significance of this model system.
Congratulations to all involved!
, 12 Jan 2022, 12(1):620, doi
