Congratulations to Diogo for securing a 4-year fellowship from the Finnish Cultural Foundation! Super-duper well done, amazing!
New antibuddy in sight!
A new intern in the lab! Thomy Garnier from Lyon, France, joined us for a 5-month internship as part of his MSc studies. He is working with Blanca to set-up dSTORM super-resolution imaging.
Celebrating personal funding!
Congratulations to Blanca and Diogo for securing graduate school funding for the whole 2023 from TuDMM and InFLAMES!
Successful PhD defense
This year’s third PhD defense from our lab was celebrated on September 31st! Congratulations, Marika Runsala (née Vainio), who successfully defended her thesis “Antigen processing and intracellular trafficking in B cells”. We are very grateful for Assoc. Prof. Zhi Jane Chen from the University Oulu , Finland, for accepting our invitation to serve as an opponent of Marika’s defense and guiding an insightful discussion on the topic.
The thesis can be found here.
All the best in the future endeavours, Marika!
Celebrating another PhD graduate
Another little bird has spread her wings! Congratulation to our very own PhD graduate from Mattila lab, Sara Hérnandez-Pérez who successfully defended his PhD thesis entitled “B Cell Activation and Antibody Responses: The role of vesicle trafficking and Rab GTPases” on August 12th. We extend our warm gratitude to her opponent Professor Balbino Alarcón from Centro de Biología Molecular Severo Ochoa (CBMSO-CSIC), Madrid, Spain, for accepting the invitation and providing such an insightful and broad discussion.
The thesis can be found here.
Sara is now starting as a posdoc on Pavel Tolar lab in the University College London – Division of Infection and Immunity (London, UK) to work on IgE BCR signalling and allergic responses.
All the best in the future endeavours!
New paper out!
New paper out!
“The SNARE protein Vti1b is recruited to the sites of BCR activation but is redundant for antigen internalisation, processing and presentation”, out in Frontiers in Cell and Developmental Biology (the article can be found through here), was a great collaboration effort between the group members and provides an awesome kick-off to the PhD projects of Blanca and Amna, who only started in the lab 1 year ago!
The study describes a SNARE protein Vti1b in the internal membranes, particularly the Golgi, of B cells with response and enrichment to the sites of BCR activation.
Massive congratulations to all involved!
Front. Cell Dev. Biol., 30 August 2022, Sec. Membrane Traffic | doi: https://doi.org/10.3389/fcell.2022.987148
New Antibuddies incoming!
Since last March, we have welcomed a new lab intern and a MSc student that will perform her thesis with us.
Anni Virtanen, currently undergoing her BSc in Biochemistry in UTU, has been a multitasking force around the lab helping in several projects and always eager to learn more and more.
Maria Tarczewska, currently performing her MSc studies in BIMA program, has been more focused on the extracellular vesicles projects and is very keen on expansion microscopy.
Welcome aboard and all the best!
Upgrading to MSc student
Our Erasmus intern Özge Balci got accepted in the MSc programme of Biomedical Imaging (joint programme between University of Turku and Åbo Akademi University) with full scholarship! Moreover, she was also granted a Finnish Scolarship for the next 2 years as the top merit applicant of the programme.
Well done and keep up the good work!
New paper published!
We are pleased to announce that our latest paper, titled “AutoCoEv-A High-Throughput In Silico Pipeline for Predicting Inter-Protein Coevolution” has been accepted for publication in the International Journal of Molecular Sciences! The article can be found through here. Accompanying scripts can be found at GitHub.
“AutoCoEv – A High-Throughput In Silico Pipeline for Predicting Inter-Protein Coevolution” offers a a user-friendly, open source, computational pipeline, that enables the search of coevolution within a large number of proteins from a predetemrined dataset. By driving 15 individual programs, culminating in CAPS2 as the software for detecting coevolution, AutoCoEv achieves a seamless automation and parallelization of the workflow. Importantly, a patch to the CAPS2 source code is provided to strengthen its statistical output, allowing for multiple comparison corrections and an enhanced analysis of the results.
Thanks to all involved!
Int.J.Mol.Sci. 2022 Mar 20;23(6):3351. doi: 10.3390/ijms23063351.
Alexey Sarapulov defended his PhD thesis in March 2022 – the first PhD graduate from Mattila’s lab!
Congratulation to our very own first PhD graduate from Mattila lab, Alexey Sarapulov who successfully defended his PhD thesis entitled “B cell-mediated immunity and signal regulation” on March 11th. We extend our warm gratitude to Professor Lars Nitschke, his opponent from Friedrich-Alexander-Universität Erlangen-Nürnberg, for accepting the invitation and for such an amazing scientific discussion.
The thesis can be found here.
Mattila’s lab members wish all the best on Alexey’s new endeavours!