Lymphocyte Activation Lab

We are pleased to announce that our latest paper, titled “B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments” has been accepted for publication in the Journal of Cell Science! The manuscript can be found here. Accompanying scripts can be found at GitHub.

Thanks for all involved!

We have submitted two papers!

Missing-In-Metastasis / Metastasis Suppressor 1 modulates B cell receptor signaling, B cell metabolic potential and T cell-independent immune responses. AV Sarapulov, P Petrov, S Hernandez-Perez, V Sustar, E Kuokkanen, M Vainio, L Cords, M Fritzsche, Y Carrasco, PK Mattila (2019) Preprint available at bioRxiv

B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments. S Hernández-Pérez*, M Vainio*, E Kuokkanen, V Sustar, P Petrov, S Fórsten, V Paavola, J Rajala, LO Awoniyi, AV Sarapulov, H Vihinen, E Jokitalo, A Bruckbauer, PK Mattila (2019) Preprint available at bioRxiv

* the authors contributed equally to the study.

“Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control” (Petrov P, Sarapulov AV, Eory L, Scielzo C, Scarfo L, Smith J, Burt DW and Mattila PK) published in Scientific Reports!

https://rdcu.be/bqnHe

Mattila Lab is on GitHub:

https://github.com/mattilalab/

Šuštar V, Vainio M, Mattila PK. Visualization and Quantitative Analysis of the Actin Cytoskeleton Upon B Cell Activation. Methods Mol Biol. 2018;1707:243-257. doi: 10.1007/978-1-4939-7474-0_18.

PubMed link: https://www.ncbi.nlm.nih.gov/pubmed/29388113